Longitudinal Oculomotor Decline Tracking

via “longitudinal-oculomotor-decline-tracking”

Unique: Applies statistical process control methods (control charts, EWMA) to individual patient baselines rather than population-level comparisons, enabling detection of patient-specific decline trajectories that may deviate from population norms due to genetic or disease heterogeneity

vs others: Provides objective, quantified disease progression metrics superior to subjective clinical rating scales (MDS-UPDRS, MMSE) which suffer from inter-rater variability and floor/ceiling effects, enabling earlier detection of therapeutic response or disease acceleration